Alcohol can lead to stomach irritation. This isn't necessarily an allergic reaction, but it's a direct reaction to a toxin of sorts. Alcohol, when it gets into the stomach, actually causes an increase in secretion of stomach acid, and that increased secretion of stomach acid can cause tenderness and belly pain. The belly pain can be treated, essentially, by trying to neutralize the acid. You could use Tums, Rolaids, or products like that, but over time it can have a disastrous effect if you continue drinking.
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